Hyperhidrosis (excessive sweating): treatment instructions

General information for patients. This page does not replace individual medical advice. Last updated 30 September 2026.

Which product

First line (over the counter):

• Underarms and body: No More Sweat Total Body spray
• Hands and feet: No More Sweat Hands & Feet spray

If not strong enough: aluminium chloride hexahydrate 20% solution, made up by a compounding pharmacy.

How to apply

1. Apply at bedtime, when sweating is at a minimum.
2. Make sure the skin is completely dry. A hair dryer on a cool setting helps, before and straight after applying.
3. Leave on for 8 hours, then wash off in the morning.

How often

• Every night until sweating improves. Significant improvement may be noticed within one week.
• Then gradually lengthen the interval between applications.
• Maintenance: usually once a week.

Avoiding irritation

• Dry skin reduces irritation and stops the product being sweated off.
• Don’t apply to broken, irritated or freshly shaved skin. Avoid shaving or hair-removal products for 12 hours before or after applying.
• If it stings or itches, apply less often. If irritation persists, see your doctor.